![]() Can you tell us about, like, how the cohorts were selected?ĮDELMAN: Yeah. RASCOE: People on hormonal contraceptives were not included in these studies. They want to know what to expect, what to experience. But we're seeing something that people want to know about. And so I want to reassure people that, really, we are not seeing a signal that's harmful. They mean that people are metabolically normal, healthy and then they also give us a look into future for fertility. You know, because menstrual cycles really mean a lot to individuals. ![]() RASCOE: And I know that this study did not look at necessarily, like, why this happened, but can you talk about - or do you - is there any sense or any guess that you might have for why this happened? And I bring this up only because, around vaccines, there's been a lot of talk about people being concerned about it affecting fertility, et cetera.ĮDELMAN: That's a great question. When we have absence of evidence, I think, in particular for women, girls and individuals who menstruate, oftentimes our concerns get downplayed. And so I want to make sure that we're validating what people are experiencing. For one day difference, it could be a big deal to some individuals, personally. And so we have a personal narrative, and it means something different to us. You know, half the population has a relationship with their menstrual period. But it could, you know, impact a person personally, right? I mean, obviously, a period is very intimate.ĮDELMAN: Yeah. RASCOE: So clinically, one day is not significant. And so it's information that we didn't have before around vaccines, and so we're pleased to be able to have that information now, so that people can know what to expect. And they were reporting that it did happen. So they - you know, we were getting a lot of the public reporting pushback that, you know, their providers were saying this couldn't be possible, this isn't happening. And then we didn't have any information to give them. But what happened at the beginning of the vaccine rollout is we just didn't have any information at all, and people were having this experience. So is this kind of extended-cycle menstruation cycle - is that harmful? Is that something to be concerned about?ĮDELMAN: So normally, no. And our study also looked at the days of bleeding that individuals have, and we didn't see an impact of COVID vaccine on the number of days of bleeding. And then the cycle post-vaccine - that clean vaccine - post-vaccine cycle - we're seeing the cycle get back to normal. We're seeing that less-than-one-day change with getting a vaccine if you get one vaccine in the cycle. RASCOE: So what did you find in this new study, you know, when you take into account, like, what happened post-vaccine, et cetera?ĮDELMAN: Yeah, so this study really confirms the findings that we had in the U.S. comparable to the data globally with different vaccines? And then we also wanted to see what happens post-vaccine. RASCOE: OK, and so did you get more expansive data in this latest study?ĮDELMAN: We really wanted to see - because this is impacting everybody globally - is our data from the U.S. What did that study find?ĮDELMAN: So that study found pretty much the same thing that we're finding in this study as well, which is that the cycle length was slightly longer - about a day - and that we weren't able, at the time, to see if it returned back to normal or when it returned back to normal. RASCOE: So this new study is building off a previous one published earlier this year, which only looked at people in the U.S. Welcome to the program.ĪLISON EDELMAN: Thanks, Ayesha. She's also the lead researcher on the newest study, and she joins us now. Alison Edelman is a professor of obstetrics and gynecology at Oregon Health & Science University. It looked at period-tracking data and did find that the COVID vaccine could affect menstrual cycle length - that is from the first day of a period through the start of the next period. But a new study published in the British Medical Journal last week has some answers. Some people have said that they noticed changes in their menstrual cycle after getting the COVID-19 vaccine, and there has been some concern over what that could mean.
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